Pramoxine Hydrochloride in Skincare
Pramoxine Hydrochloride is an FDA-approved active that temporarily relieves itching associated with minor skin irritations.
SKIN NOTES - THE SKINCARE BLOG
Welcome to Prequel's Skin Notes.
As a dermatologist-developed brand, we're passionate about skin health education. Skin Notes is a skincare blog that focuses on skin concerns, efficacious ingredients, new technologies and more.
TIPS + ADVICE
SKIN TYPES
SKIN CONCERNS
INGREDIENT LOG
Prequel Skincare Routine for Rosacea-Prone Skin
A simple, consistent skincare routine for rosacea-prone skin helps minimize irritation and support overall skin comfort. Each step focuses on cleansing, calming, hydration, and daily protection. A consistent, low-irritation routine helps support skin comfort and reduce visible redness over time.Â
Prequel Skincare Routine for Eczema-Prone Skin
A skincare routine for eczema-prone skin should focus on gentle cleansing, hydration, moisturizing consistently, and protecting areas that feel dry or irritated. Eczema-prone skin benefits from a routine built around hydration, barrier support, and protection. Gentle cleansing, hydrating serums, moisturizers, and skin protectants can help reduce dryness and support overall comfort.
Prequel Skincare Routine for Psoriasis-Prone Skin
A skincare routine for psoriasis-prone skin should focus on cleansing gently, replenishing hydration, softening rough texture, and protecting areas that feel dry or compromised. A consistent routine focused on hydration, gentle smoothing, and barrier support helps maintain skin comfort over time. Using a moisturizer that both hydrates and softens rough texture, along with protective steps when needed, can help improve how skin feels and looks. Â
The Complete Guide to Moisturizers
A moisturizer is a cosmetic product designed to increase skin hydration, reduce transepidermal water loss (TEWL), and support skin barrier function. They work by increasing water content within the stratum corneum while reinforcing the lipid matrix that helps retain moisture. Understanding how moisturizers perform can help you determine which are best for your skin. Â
The Complete Guide to Skin Protectants
When the barrier is functioning well, skin feels more comfortable, less reactive, and more resilient. Skin protectants are one of the tools available to support that process when reinforcement is needed: They are formulated with FDA-approved active ingredients designed to temporarily protect compromised skin and reduce moisture loss.
Alpha Arbutin in Skincare
Alpha Arbutin helps reduce the look of uneven tone for a brighter looking complexion.
Hexylresorcinol in Skincare
Hexylresorcinol is a clinically proven, well-tolerated skin-brightening antioxidant that helps improve uneven skin tone.
Acetyl Glucosamine in Skincare
Acetyl Glucosamine is a multi-purpose antioxidant known to help fade the look of discoloration
Everything to Know About Redness Reform Sulfur Cleanser
Our new Redness Reform Sulfur Cleanser delivers the clarifying and calming benefits of sulfur in the form of an ultra-plush, gentle formula that leaves skin feeling soothed and hydrated. And it’s clinically proven to perform well on rosacea-prone skin.
Colloidal Sulfur in Skincare
Colloidal Sulfur Colloidal sulfur is a potent, nano-sized form of sulfur that is well-studied for its ability to clarify and soothe redness-prone skin. The colloidal sulfur in our Redness Reform cleanser is suspended in a protective Acacia senegal gum colloid, which helps keep the tiny sulfur particles stable and separated—improving absorption, efficacy, and dispersion. (It also has the added benefit of reducing sulfur’s natural odor.) We're always adding more ingredient information - check back later for more on this ingredient.
Everything To Know About Our Barrier Therapy Skin Protectant Creams
Our Barrier Therapy Skin Protectant Cream for face and body is part of Prequel's skin protectants collection, a drug category identified by the FDA meant to protect injured or exposed skin from harmful or annoying stimuli while helping to provide relief to the skin. Containing 1% Colloidal Oatmeal, our Barrier Therapy Skin Protectant Cream addresses dryness, eczema flare-ups, and atopic dermatitis.
Everything to Know About Multi-Quench Hydration Mist
Hydration is the foundation of a healthy skin barrier. Building on our love of the Multi-Quench Polyglutamic Acid Serum, we wanted to create a mist version to help refresh hydration —and add radiance—throughout the day. The result is a lightweight formula that's as effective as a serum. It’s a new on-the-go essential for keeping skin hydrated, refreshed, and glowy all day long.
Pure PGA + PGA Complex in Skincare
Pure PGA + PGA Complex is a multi-molecular weight polyglutamic acid blend that enhances skin moisture retention and helps increase the production of natural moisturizing factors (NMF) for plumper, smoother skin.
Glycerin And Aloe
Glycerin + Aloe are osmolytes that improve skin hydration, enhance surface elasticity, and soothe.
SKIN NOTES
DISCLAIMER:
All skincare blog posts are intended to help educate on specific ingredients and skin care topics. Our articles are written to be informative and informational. They are not indicative of individual performance. Results may vary per applicant. Any reference to a specific patient experience is not a medical suggestion for treatment. Please note that any Prequel products with referenced ingredients are formulated for Cosmetic Use Only and NOT intended as replacements for physician advice and/or pharmaceutical product recommendations.
